|Mouse neurons labeled with fluorescent tags|
by Stephen J Smith
In the recent Nature Genetics paper entitled: 'The integrated landscape of driver genomic alterations in glioblastoma' the authors describe an approach which identified 33 different driver genes that are responsible for the most prevalent and aggressive form of brain cancer. The majority of these genes are not currently targets of any available drugs. However, when drugs become available the authors envision personalized glioblastoma treatment becoming a reality. This would involve identification of which driver gene is responsible for the individuals brain cancer and then application of the appropriate treatment.
The search for inhibitors of these driver genes is possible with appropriate assay design and analysis both of which are possible with the multimode readers available from BMG LABTECH. Please visit our website (www.bmglabtech.com) to find out more about the capabilities of our microplate readers.