|AlphaScreen measurement of activated |
Gi and Gq coupled GPGR's
In application note 210 from BMG LABTECH this approach was used to produce dose response curves for Gi and Gq G-protein coupled receptor agonists in a 384 well format using the POLARstar Omega. Although the POLARstar Omega does not have a laser for excitation, the use of AlphaScreen optimized filters allow this microplate reader to consistently attain sensitive results.
For more information on this and other applications for all of the microplate readers that BMG LABTECH has to offer please visit the applications center on our web site.